Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL347384 | 0.91 | HIF1A (0.47) | HIF1ALMNASMN1; SMN2KDM4EHTT | |
| SCHEMBL18068171 | 0.88 | HIF1A (0.46) | HIF1ALMNASMN1; SMN2KDM4EHTT | |
| SCHEMBL15834618 | 0.84 | HIF1A (0.43) | HIF1ALMNASMN1; SMN2KDM4EHTT | |
| SCHEMBL14507015 | 0.84 | HSD17B10 (0.56) | HIF1ALMNASMN1; SMN2KDM4EHTT | |
| SCHEMBL17373112 | 0.84 | HIF1A (0.43) | HIF1ALMNASMN1; SMN2KDM4EHTT | |
| SCHEMBL17269974 | 0.84 | HIF1A (0.43) | HIF1ALMNASMN1; SMN2KDM4EHTT | |
| SCHEMBL325805 | 0.83 | KDM4E (0.52) | KDM4EHTTHSD17B10HPGDUSP2 | |
| SCHEMBL11913778 | 0.82 | USP2 (0.48) | HIF1ALMNASMN1; SMN2KDM4EHTT | |
| SCHEMBL10001677 | 0.81 | HSD17B10 (0.46) | HIF1ALMNASMN1; SMN2KDM4EHTT | |
| SCHEMBL19616476 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3142772-B1 | ABSORBENT SOLUTION BASED ON BETA-HYDROXYLATED TERTIARY DIAMINES AND PROCESS FOR ELIMINATING ACID COMPOUNDS FROM A GASEOUS EFFLUENT | IFP ENERGIES NOW (FR) | 2018-04-11 | — | — | EP | disclosed |