Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.45 |
| ▸ | RAB9A | P51151 | 7/20 | 0.45 |
| ▸ | TP53 | P04637 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | CASP3 | P42574 | 2/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17507364 | 0.99 | NPC1 (0.44) | NPC1RAB9ATP53MAPTHPGD | |
| SCHEMBL20041655 | 0.90 | TP53 (0.45) | NPC1RAB9ATP53MAPTHPGD | |
| SCHEMBL17507250 | 0.89 | TP53 (0.44) | NPC1RAB9ATP53MAPTHPGD | |
| SCHEMBL20041610 | 0.88 | NPC1 (0.51) | NPC1RAB9ATP53MAPTHPGD | |
| SCHEMBL17507363 | 0.88 | NPC1 (0.54) | NPC1RAB9ATP53MAPTHPGD | |
| SCHEMBL17507245 | 0.86 | NPC1 (0.51) | NPC1RAB9ATP53MAPTHPGD | |
| SCHEMBL20041422 | 0.85 | NPC1 (0.44) | NPC1RAB9ATP53MAPTHPGD | |
| SCHEMBL20041552 | 0.84 | NPC1 (0.41) | NPC1RAB9ATP53MAPTHPGD | |
| SCHEMBL22357700 | 0.83 | NPC1 (0.49) | NPC1RAB9AMAPTHPGDSMN1; SMN2 | |
| SCHEMBL18701303 | 0.82 | NPC1 (0.46) | NPC1RAB9ATP53MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2982676-B1 | Benzimidazo[2,1-B]benzoxazoles for electronic applications | IDEMITSU KOSAN CO (JP) | 2018-04-11 | — | — | EP | disclosed |