⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12482372 | 0.74 | — | — | |
| SCHEMBL24583200 | 0.74 | — | — | |
| SCHEMBL24034394 | 0.73 | — | — | |
| SCHEMBL23393546 | 0.73 | — | — | |
| SCHEMBL19265749 | 0.71 | — | — | |
| SCHEMBL22950601 | 0.71 | — | — | |
| SCHEMBL19336088 | 0.69 | — | — | |
| SCHEMBL8117320 | 0.68 | — | — | |
| SCHEMBL23395390 | 0.65 | — | — | |
| SCHEMBL23714610 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3825314-A1 | AZAINDOLE DERIVATIVE AND USE THEREOF AS FGFR AND C-MET INHIBITOR | Medshine Discovery Inc. (CN) | 2021-05-26 | — | — | EP | disclosed |
| WO-2020015744-A1 | AZAINDOLE DERIVATIVE AND USE THEREOF AS FGFR AND C-MET INHIBITOR | 南京明德新药研发有限公司 | 2020-01-23 | — | — | WO | disclosed |
| EP-3305073-A1 | 1H-PYRAZOLO[3,4-B]PYRIDINES AND THERAPEUTIC USES THEREOF | Samumed, LLC (US) | 2018-04-11 | — | — | EP | disclosed |