Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.53 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.53 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.48 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.48 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | F2RL1 | P55085 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16785390 | 1.00 | PDE4A (0.53) | PDE4APDE4BPDE4CPDE4DDDB1 | |
| SCHEMBL29434258 | 1.00 | PDE4A (0.53) | PDE4APDE4BPDE4CPDE4DDDB1 | |
| SCHEMBL16785409 | 0.88 | DDB1 (0.49) | PDE4APDE4BPDE4CPDE4DDDB1 | |
| SCHEMBL18106605 | 0.84 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4DDDB1 | |
| SCHEMBL18117707 | 0.84 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4DDDB1 | |
| SCHEMBL16785489 | 0.84 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4DDDB1 | |
| SCHEMBL16785350 | 0.84 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4DDDB1 | |
| SCHEMBL29434235 | 0.84 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4DDDB1 | |
| SCHEMBL19559436 | 0.84 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4DDDB1 | |
| SCHEMBL16785349 | 0.84 | KDM4E (0.53) | PDE4APDE4BPDE4CPDE4DKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305763-A1 | DEUTERATED OR ISOTOPICALLY LABELED UREA DERIVATIVES OR PHARMACOLOGICALLY ACCEPTABLE SALTS THEREOF USEFUL AS FPRL-1 AGONISTS | Kyorin Pharmaceutical Co., Ltd. (JP) | 2018-04-11 | — | — | EP | disclosed |