SCHEMBL20041927

SCHEMBL20041927

c1ccc2c(c1)nc(-n1c3ccc(-n4c5ccccc5c5ccccc54)cc3c3cc(-n4c5ccccc5c5ccccc54)ccc31)n1c3ccccc3nc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.50
MAPT P10636 5/20 0.50
LMNA P02545 3/20 0.50
POLB P06746 3/20 0.50
TP53 P04637 2/20 0.50
HSD17B10 Q99714 2/20 0.50
HPGD P15428 7/20 0.49
ALDH1A1 P00352 7/20 0.49
KMT2A Q03164 4/20 0.47
MEN1 O00255 3/20 0.47
SMN1; SMN2 Q16637 3/20 0.44
GAA P10253 1/20 0.40
HIF1A Q16665 1/20 0.40
ATM Q13315 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
NPC1 O15118 1/20 0.38
NFKB1 P19838 1/20 0.38
NFKB2 Q00653 1/20 0.38
RELA Q04206 1/20 0.38
CAMKK1 Q8N5S9 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20042000 1.00 KDM4E (0.50) KDM4EMAPTLMNAPOLBTP53
SCHEMBL20151020 0.93 KDM4E (0.49) KDM4EMAPTLMNAPOLBTP53
SCHEMBL20151435 0.92 KDM4E (0.50) KDM4EMAPTLMNAPOLBTP53
SCHEMBL20151464 0.92 KDM4E (0.50) KDM4EMAPTLMNAPOLBTP53
SCHEMBL20151039 0.92 KDM4E (0.43) KDM4EMAPTLMNAPOLBTP53
SCHEMBL20151022 0.91 KDM4E (0.42) KDM4EMAPTLMNAPOLBTP53
SCHEMBL20151038 0.90 KDM4E (0.48) KDM4EMAPTLMNAPOLBTP53
SCHEMBL20151165 0.90 KDM4E (0.43) KDM4EMAPTLMNAPOLBTP53
SCHEMBL20151044 0.89 KDM4E (0.50) KDM4EMAPTLMNAPOLBTP53
SCHEMBL20151060 0.89 KDM4E (0.50) KDM4EMAPTLMNAPOLBTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11031560-B2 Compound and organic electronic element comprising same LG CHEM, LTD. (KR) 2021-06-08 US disclosed
EP-3305775-B1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG CHEMICAL LTD (KR) 2019-08-28 EP disclosed
US-20180138422-A1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-05-17 US disclosed
US-20180138422-A1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-05-17 US disclosed
EP-3305775-A2 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG Chem, Ltd. (KR) 2018-04-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11031560-B2 Compound and organic electronic element comprising same OR10J3, ESR1, ETV6 KDM4E 847/4885MAPT 1791/4885LMNA 4004/4885
US-20180138422-A1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME OR10J3, ESR1, ETV6 KDM4E 847/4885MAPT 1791/4885LMNA 4004/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.