SCHEMBL20042454

SCHEMBL20042454

CC1(C)c2cc(-c3ccc(C=C(C#N)C#N)c4nsnc34)sc2-c2sc3c4c(sc3c21)-c1sc(-c2ccc(C=C(C#N)C#N)c3nsnc23)cc1C4(C)C

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
TNNI3 P19429 1/20 0.31
TNNT2 P45379 1/20 0.31
TNNC1 P63316 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20042511 0.94
SCHEMBL20042451 0.87 APP (0.31) MEN1LMNATNNI3TNNT2TNNC1
SCHEMBL20042453 0.86 APP (0.31)
SCHEMBL20042507 0.86 APP (0.31)
SCHEMBL20042531 0.85 MAPT (0.32) MEN1LMNATNNI3TNNT2TNNC1
SCHEMBL20042485 0.84 MEN1 (0.30) MEN1LMNATNNI3TNNT2TNNC1
SCHEMBL20042483 0.84
SCHEMBL20042450 0.83
SCHEMBL20042509 0.82
SCHEMBL20042512 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3523308-B1 ORGANIC SEMICONDUCTING COMPOUNDS RAYNERGY TEK INC (TW) 2023-09-06 EP disclosed
US-10991893-B2 Organic semiconducting compounds Raynergy Tek Incorporation (TW) 2021-04-27 US disclosed
US-20200052227-A1 ORGANIC SEMICONDUCTING COMPOUNDS MERCK PATENT GMBH (DE) 2020-02-13 US disclosed
WO-2018065350-A1 ORGANIC SEMICONDUCTING COMPOUNDS MERCK PATENT GMBH (DE) 2018-04-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200052227-A1 ORGANIC SEMICONDUCTING COMPOUNDS OCIAD2, OCIAD1, OSTC MEN1 2805/4885LMNA 4414/4885TNNI3 4673/4885
US-10991893-B2 Organic semiconducting compounds OCIAD2, OCIAD1, OSTC MEN1 2805/4885LMNA 4414/4885TNNI3 4673/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.