Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | APP | P05067 | 4/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | PRMT1 | Q99873 | 4/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | FOLR1 | P15328 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19485425 | 0.88 | MAPT (0.51) | MAPTAPPHDAC3HDAC1HDAC6 | |
| SCHEMBL19485423 | 0.83 | MAPT (0.46) | MAPTAPPHDAC3HDAC1HDAC6 | |
| SCHEMBL12713683 | 0.82 | PRMT1 (0.53) | MAPTAPPPRMT1PRMT5CARM1 | |
| SCHEMBL13898267 | 0.82 | PRMT1 (0.45) | MAPTAPPPRMT1PRMT5CARM1 | |
| SCHEMBL14597380 | 0.81 | PRMT1 (0.52) | MAPTAPPPRMT1PRMT5CARM1 | |
| SCHEMBL31673509 | 0.81 | PRMT1 (0.52) | MAPTAPPPRMT1PRMT5CARM1 | |
| SCHEMBL14597383 | 0.81 | PRMT1 (0.52) | MAPTAPPPRMT1PRMT5CARM1 | |
| SCHEMBL13898147 | 0.81 | PRMT1 (0.52) | MAPTAPPPRMT1PRMT5CARM1 | |
| SCHEMBL12364494 | 0.79 | PRMT1 (0.53) | MAPTAPPPRMT1PRMT5CARM1 | |
| SCHEMBL5181135 | 0.79 | PRMT1 (0.53) | MAPTAPPPRMT1PRMT5CARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180099934-A1 | PSMA-TARGETED NIR DYES AND THEIR USES | On Target Laboratories, Inc. | 2018-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180099934-A1 | PSMA-TARGETED NIR DYES AND THEIR USES | FOLH1, KLK3, PSMA6 | MAPT 969/4885APP 1615/4885HDAC3 2789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.