⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1496278 | 0.68 | — | — | |
| SCHEMBL19364731 | 0.65 | HCAR2 (0.46) | — | |
| SCHEMBL24867761 | 0.65 | AXL (0.43) | — | |
| SCHEMBL24175286 | 0.65 | — | — | |
| SCHEMBL13066528 | 0.63 | AXL (0.68) | — | |
| SCHEMBL25435877 | 0.61 | AXL (0.40) | — | |
| SCHEMBL11267090 | 0.61 | — | — | |
| SCHEMBL9735156 | 0.59 | — | — | |
| SCHEMBL19805377 | 0.56 | — | — | |
| SCHEMBL16709916 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180099940-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ANDROGEN RECEPTOR | ARVINAS OPERATIONS, INC. | 2018-04-12 | — | — | US | disclosed |