SCHEMBL20046965

SCHEMBL20046965

CC(C)N1CCC2(CC1)CC(F)C2

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.37
HRH3 Q9Y5N1 6/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12827764 0.80 CYP2D6 (0.38) CYP2D6HRH3
SCHEMBL24033706 0.80 CYP2D6 (0.38) CYP2D6HRH3
SCHEMBL18712889 0.78 CYP2D6 (0.37) CYP2D6HRH3
SCHEMBL12748283 0.78 CYP2D6 (0.37) CYP2D6HRH3
SCHEMBL20088234 0.78 HRH3 (0.39) CYP2D6HRH3
SCHEMBL20147717 0.78 CYP2D6 (0.41) CYP2D6HRH3
SCHEMBL10111445 0.78 CYP2D6 (0.46) CYP2D6HRH3
SCHEMBL27272098 0.77
SCHEMBL24623594 0.77 CYP2D6 (0.36) CYP2D6HRH3
SCHEMBL7770721 0.76 CYP2D6 (0.45) CYP2D6HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018067615-A1 COMPOUNDS, DEVICES, AND USES THEREOF SIGILON THERAPEUTICS, INC. (US) 2018-04-12 WO disclosed