⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16099013 | 0.91 | — | — | |
| SCHEMBL23794065 | 0.90 | — | — | |
| SCHEMBL3484368 | 0.88 | — | — | |
| SCHEMBL11792136 | 0.88 | — | — | |
| SCHEMBL20047192 | 0.85 | — | — | |
| SCHEMBL17705614 | 0.83 | — | — | |
| SCHEMBL13072613 | 0.79 | — | — | |
| SCHEMBL13072281 | 0.75 | — | — | |
| SCHEMBL31048904 | 0.71 | — | — | |
| SCHEMBL11472507 | 0.70 | KDM4C (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200039943-A1 | COMPOUNDS, DEVICES, AND USES THEREOF | SIGILON THERAPEUTICS, INC. | 2020-02-06 | — | — | US | disclosed |
| WO-2018067615-A1 | COMPOUNDS, DEVICES, AND USES THEREOF | SIGILON THERAPEUTICS, INC. (US) | 2018-04-12 | — | — | WO | disclosed |