Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17774455 | 0.82 | SMN1; SMN2 (0.33) | SMN1; SMN2 | |
| SCHEMBL13434962 | 0.82 | SMN1; SMN2 (0.33) | SMN1; SMN2 | |
| SCHEMBL2650942 | 0.64 | — | — | |
| SCHEMBL5924132 | 0.64 | — | — | |
| SCHEMBL27035890 | 0.64 | CA1 (0.35) | SMN1; SMN2 | |
| SCHEMBL3821916 | 0.62 | SMN1; SMN2 (0.36) | SMN1; SMN2 | |
| SCHEMBL13105435 | 0.61 | SMN1; SMN2 (0.40) | SMN1; SMN2 | |
| SCHEMBL13120290 | 0.61 | SMN1; SMN2 (0.40) | SMN1; SMN2 | |
| SCHEMBL12601231 | 0.59 | SMN1; SMN2 (0.33) | SMN1; SMN2 | |
| SCHEMBL5924334 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018065962-A1 | SUBSTITUTED PYRROLIDINES AND THEIR USE IN THE TREATMENT OF CYSTIC FIIBROSIS | AbbVie S.à.r.l. (LU) | 2018-04-12 | — | — | WO | disclosed |