Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13587142 | 0.81 | — | — | |
| SCHEMBL20047529 | 0.77 | — | — | |
| SCHEMBL14970054 | 0.76 | HSD17B10 (0.33) | USP2ALOX15APOBEC3AHSD17B10APOBEC3G | |
| SCHEMBL1673946 | 0.73 | USP2 (0.32) | USP2ALOX15APOBEC3AHSD17B10APOBEC3G | |
| SCHEMBL7990997 | 0.73 | USP2 (0.32) | USP2ALOX15APOBEC3AHSD17B10APOBEC3G | |
| SCHEMBL16268335 | 0.70 | USP2 (0.33) | USP2ALOX15APOBEC3AHSD17B10APOBEC3G | |
| SCHEMBL6844986 | 0.70 | KDM4E (0.34) | USP2ALOX15APOBEC3AHSD17B10APOBEC3G | |
| SCHEMBL13666783 | 0.68 | POLB (0.41) | HSD17B10 | |
| SCHEMBL17339855 | 0.67 | HSD17B10 (0.35) | USP2ALOX15APOBEC3AHSD17B10APOBEC3G | |
| SCHEMBL814058 | 0.67 | HSD17B10 (0.33) | USP2ALOX15APOBEC3AHSD17B10APOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018067704-A1 | ISOXAZOLE ANALOGS AS FXR AGONISTS AND METHODS OF USE THEREOF | ENANTA PHARMACEUTICALS, INC. (US) | 2018-04-12 | — | — | WO | disclosed |