Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 17/20 | 0.67 |
| ▸ | ACHE | P22303 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20049542 | 0.90 | STING1 (0.76) | STING1ACHE | |
| SCHEMBL20049446 | 0.89 | STING1 (0.80) | STING1 | |
| SCHEMBL20022205 | 0.89 | STING1 (0.80) | STING1ACHE | |
| SCHEMBL20049525 | 0.87 | STING1 (0.65) | STING1 | |
| SCHEMBL21452544 | 0.85 | STING1 (0.80) | STING1ACHE | |
| SCHEMBL21452861 | 0.85 | STING1 (0.77) | STING1ACHE | |
| SCHEMBL20049659 | 0.85 | STING1 (0.79) | STING1ACHE | |
| SCHEMBL20022272 | 0.84 | STING1 (0.68) | STING1 | |
| SCHEMBL29636418 | 0.84 | STING1 (0.68) | STING1 | |
| SCHEMBL21452559 | 0.83 | STING1 (0.63) | STING1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018067423-A1 | BENZO[b]THIOPHENE COMPOUNDS AS STING AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2018-04-12 | — | — | WO | disclosed |