SCHEMBL20049533

SCHEMBL20049533

COC(=O)c1ccc(OCC(COc2ccc(C(=O)OC)cc2)(COc2ccc(C(=O)OC)cc2)COc2ccc(C(=O)OC)cc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.70
RAB9A P51151 6/20 0.62
CA1 P00915 2/20 0.60
CA2 P00918 2/20 0.60
NPC1 O15118 5/20 0.57
SMN1; SMN2 Q16637 4/20 0.57
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
TDP1 Q9NUW8 2/20 0.53
LMNA P02545 2/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
GAA P10253 1/20 0.53
CA12 O43570 1/20 0.52
CA7 P43166 1/20 0.52
CA9 Q16790 1/20 0.52
CA14 Q9ULX7 1/20 0.52
LOXL2 Q9Y4K0 1/20 0.50
POLB P06746 1/20 0.50
BLM P54132 1/20 0.50
STS P08842 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20487185 0.93 MAPT (0.62) MAPTRAB9ACA1CA2NPC1
SCHEMBL13366190 0.87 MAPT (0.68) MAPTRAB9ACA1CA2NPC1
SCHEMBL13366140 0.86 MAPT (0.66) MAPTRAB9ACA1CA2NPC1
SCHEMBL10498948 0.86 MAPT (0.66) MAPTRAB9ACA1CA2NPC1
SCHEMBL5153032 0.83 MAPT (0.62) MAPTRAB9ACA1CA2NPC1
SCHEMBL1951546 0.82 MAPT (1.00) MAPTRAB9ACA1CA2NPC1
SCHEMBL21811085 0.82 MAPT (0.60) MAPTRAB9ACA1CA2NPC1
SCHEMBL2469151 0.81 MAPT (0.89) MAPTRAB9ACA1CA2NPC1
SCHEMBL204175 0.81 MAPT (0.75) MAPTRAB9ACA1CA2NPC1
SCHEMBL10295156 0.81 MAPT (0.75) MAPTRAB9ACA1CA2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3458183-B1 SELECTIVELY PERMEABLE GRAPHENE OXIDE MEMBRANE NITTO DENKO CORP (JP) 2022-08-24 EP disclosed
EP-3589390-B1 SELECTIVELY PERMEABLE GRAPHENE OXIDE MEMBRANE NITTO DENKO CORP (JP) 2022-08-17 EP disclosed
US-20210178336-A1 SELECTIVELY PERMEABLE GRAPHENE OXIDE MEMBRANE NITTO DENKO CORPORATION (JP) 2021-06-17 US disclosed
US-20200261861-A1 SELECTIVELY PERMEABLE GRAPHENE OXIDE MEMBRANE NITTO DENKO CORPORATION (JP) 2020-08-20 US disclosed
WO-2018160871-A2 SELECTIVELY PERMEABLE GRAPHENE OXIDE MEMBRANE NITTO DENKO CORPORATION (JP) 2018-09-07 WO disclosed
WO-2018067269-A1 GRAPHENE OXIDE ANTI-MICROBIAL ELEMENT NITTO DENKO CORPORATION (JP) 2018-04-12 WO disclosed