Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15114145 | 0.81 | — | — | |
| SCHEMBL19074013 | 0.77 | — | — | |
| SCHEMBL15114160 | 0.74 | — | — | |
| SCHEMBL2133474 | 0.73 | — | — | |
| SCHEMBL13362893 | 0.71 | TSHR (0.46) | TSHR | |
| SCHEMBL23324830 | 0.71 | — | — | |
| SCHEMBL15114149 | 0.70 | — | — | |
| SCHEMBL23132019 | 0.70 | — | — | |
| SCHEMBL8367425 | 0.68 | — | — | |
| SCHEMBL25734657 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018067786-A1 | SUBSTITUTED 1H-IMIDAZO[4,5-B]PYRIDIN-2(3H)-ONES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-04-12 | — | — | WO | disclosed |