SCHEMBL20051416

SCHEMBL20051416

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nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14293621 0.88 AR (0.32) AR
SCHEMBL24037081 0.88 AR (0.32) AR
SCHEMBL24093807 0.82
SCHEMBL26027605 0.74
SCHEMBL25795565 0.73
SCHEMBL23084214 0.73
SCHEMBL11996748 0.72 AR (0.30) AR
SCHEMBL2555632 0.71
SCHEMBL24912908 0.70
SCHEMBL13452824 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230158152-A1 PROTEOLYSIS REGULATOR AND METHOD FOR USING SAME MEDSHINE DISCOVERY INC. (CN) 2023-05-25 US disclosed
WO-2022204184-A1 ANTI-CANCER NUCLEAR HORMONE RECEPTOR-TARGETING COMPOUNDS NUVATION BIO INC. (US) 2022-09-29 WO disclosed
EP-3522933-B1 METHODS FOR PREPARING ANTIBODY DRUG CONJUGATES HOFFMANN LA ROCHE (CH) 2021-12-15 EP disclosed
WO-2018065501-A1 METHODS FOR PREPARING ANTIBODY DRUG CONJUGATES F. HOFFMANN-LA ROCHE AG (CH) 2018-04-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230158152-A1 PROTEOLYSIS REGULATOR AND METHOD FOR USING SAME PSMA6, PSMC1, PSMA1 AR 1545/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.