Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MLYCD | O95822 | 2/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16777057 | 0.91 | GRM3 (0.39) | HRH3KMT2AMCHR1HDAC4 | |
| SCHEMBL16777056 | 0.91 | GRM3 (0.39) | HRH3KMT2AMCHR1HDAC4 | |
| SCHEMBL21534969 | 0.89 | MCHR1 (0.33) | HRH3MCHR1 | |
| SCHEMBL20053591 | 0.84 | HRH3 (0.43) | HRH3HPGDMEN1TSHRKMT2A | |
| SCHEMBL20053587 | 0.82 | HRH3 (0.42) | HRH3HPGDMEN1TSHRKMT2A | |
| SCHEMBL15537980 | 0.81 | GRM3 (0.38) | HRH3KMT2AALDH1A1SMN1; SMN2HDAC4 | |
| SCHEMBL15537978 | 0.81 | GRM3 (0.38) | HRH3KMT2AALDH1A1SMN1; SMN2HDAC4 | |
| SCHEMBL21042670 | 0.80 | HRH3 (0.52) | HRH3HPGDMEN1KMT2AADRB2 | |
| SCHEMBL16803779 | 0.79 | GRM3 (0.41) | HRH3CHKA | |
| SCHEMBL15560215 | 0.79 | KMT2A (0.38) | HRH3KMT2AHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944600-B2 | Piperidine derivatives for GPR119 agonist | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2018-04-17 | — | — | US | disclosed |