Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.40 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 5/20 | 0.40 |
| ▸ | VNN1 | O95497 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20053705 | 0.97 | PDK2 (0.40) | PDK2SPHK1SPHK2DPP4VNN1 | |
| SCHEMBL15539597 | 0.88 | PDK2 (0.42) | PDK2DPP4HTR1AHTR7 | |
| SCHEMBL15540105 | 0.88 | PDK2 (0.42) | PDK2DPP4HTR1AHTR7 | |
| SCHEMBL16803933 | 0.87 | DPP4 (0.41) | PDK2SPHK1SPHK2DPP4VNN1 | |
| SCHEMBL15539668 | 0.86 | HCRTR1 (0.40) | PDK2DPP4HTR1AHTR7 | |
| SCHEMBL15538724 | 0.86 | HCRTR1 (0.40) | PDK2DPP4HTR1AHTR7 | |
| SCHEMBL18849074 | 0.85 | SPHK2 (0.49) | PDK2SPHK1SPHK2 | |
| SCHEMBL16803935 | 0.84 | JAK2 (0.40) | SPHK1SPHK2DPP4VNN1HTR1A | |
| SCHEMBL16803879 | 0.84 | PDK2 (0.43) | PDK2SPHK1SPHK2DPP4VNN1 | |
| SCHEMBL15538880 | 0.84 | SSTR5 (0.47) | SSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944600-B2 | Piperidine derivatives for GPR119 agonist | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2018-04-17 | — | — | US | disclosed |