Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 18/20 | 0.46 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20054015 | 0.90 | BTK (0.47) | BTK | |
| SCHEMBL20054022 | 0.90 | BTK (0.48) | BTK | |
| SCHEMBL20054013 | 0.90 | BTK (0.49) | BTK | |
| SCHEMBL21168787 | 0.85 | BTK (0.46) | BTKAAK1 | |
| SCHEMBL16794257 | 0.79 | BTK (0.51) | BTK | |
| SCHEMBL16814192 | 0.79 | BTK (0.41) | BTK | |
| SCHEMBL16814195 | 0.78 | BTK (0.40) | BTK | |
| SCHEMBL16793965 | 0.77 | BTK (0.45) | BTK | |
| SCHEMBL16794062 | 0.77 | BTK (0.43) | BTK | |
| SCHEMBL16794275 | 0.77 | BTK (0.43) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3080103-B1 | BIARYL COMPOUNDS USEFUL FOR THE TREATMENT OF HUMAN DISEASES IN ONCOLOGY, NEUROLOGY AND IMMUNOLOGY | BIOGEN MA INC (US) | 2018-04-18 | — | — | EP | disclosed |