Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20054126 | 0.94 | PTPN1 (0.38) | PTPN1SMN1; SMN2ALDH1A1GAAHPGD | |
| SCHEMBL20054138 | 0.90 | PTPN1 (0.40) | PTPN1SMN1; SMN2ALDH1A1GAAHPGD | |
| SCHEMBL19388214 | 0.80 | CETP (0.34) | PTPN1SMN1; SMN2ALDH1A1GAATP53 | |
| SCHEMBL20054162 | 0.79 | PTPN1 (0.42) | PTPN1SMN1; SMN2ALDH1A1GAAHPGD | |
| SCHEMBL15116433 | 0.79 | SMN1; SMN2 (0.35) | PTPN1SMN1; SMN2ALDH1A1GAATP53 | |
| SCHEMBL15116428 | 0.78 | SMN1; SMN2 (0.34) | PTPN1SMN1; SMN2ALDH1A1GAATP53 | |
| SCHEMBL15125068 | 0.78 | SMN1; SMN2 (0.35) | PTPN1SMN1; SMN2ALDH1A1GAAHPGD | |
| SCHEMBL15113165 | 0.78 | SMN1; SMN2 (0.34) | PTPN1SMN1; SMN2ALDH1A1GAAHPGD | |
| SCHEMBL15125084 | 0.77 | SMN1; SMN2 (0.36) | PTPN1SMN1; SMN2ALDH1A1GAATP53 | |
| SCHEMBL5112211 | 0.76 | CNR2 (0.36) | SMN1; SMN2ALDH1A1GAATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3019196-B1 | COMBINATIONS OF HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-06-06 | — | — | EP | disclosed |
| EP-2802326-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-04-18 | — | — | EP | disclosed |