Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20221694 | 1.00 | NR1H2 (0.41) | NR1H2TSHRCHRM2CHRM1CHRM3 | |
| SCHEMBL16994161 | 1.00 | NR1H2 (0.41) | NR1H2TSHRCHRM2CHRM1CHRM3 | |
| SCHEMBL20811182 | 1.00 | NR1H2 (0.41) | NR1H2TSHRCHRM2CHRM1CHRM3 | |
| SCHEMBL16994173 | 1.00 | NR1H2 (0.41) | NR1H2TSHRCHRM2CHRM1CHRM3 | |
| SCHEMBL15116890 | 1.00 | NR1H2 (0.41) | NR1H2TSHRCHRM2CHRM1CHRM3 | |
| SCHEMBL2542298 | 1.00 | NR1H2 (0.41) | NR1H2TSHRCHRM2CHRM1CHRM3 | |
| SCHEMBL17711418 | 0.85 | CHRM2 (0.42) | NR1H2CHRM2CHRM1CHRM3USP2 | |
| SCHEMBL17711417 | 0.85 | CHRM2 (0.42) | NR1H2CHRM2CHRM1CHRM3USP2 | |
| SCHEMBL527701 | 0.83 | TSHR (0.56) | NR1H2TSHRCHRM2CHRM1CHRM3 | |
| SCHEMBL344752 | 0.83 | TSHR (0.56) | NR1H2TSHRCHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3019196-B1 | COMBINATIONS OF HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-06-06 | — | — | EP | disclosed |
| EP-2802326-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-04-18 | — | — | EP | disclosed |