Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 8/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 8/20 | 0.48 |
| ▸ | WNT1 | P04628 | 6/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | MELK | Q14680 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20054445 | 1.00 | GSK3B (0.48) | GSK3BDYRK1AWNT1HDAC3HDAC1 | |
| SCHEMBL20054523 | 0.95 | GSK3B (0.53) | GSK3BDYRK1AWNT1HDAC3HDAC1 | |
| SCHEMBL20221305 | 0.94 | GSK3B (0.44) | GSK3BDYRK1AWNT1HDAC3HDAC1 | |
| SCHEMBL20054351 | 0.92 | GSK3B (0.43) | GSK3BDYRK1AWNT1PDPK1AAK1 | |
| SCHEMBL20054393 | 0.91 | GSK3B (0.43) | GSK3BDYRK1AWNT1HDAC3HDAC1 | |
| SCHEMBL20054417 | 0.87 | GSK3B (0.49) | GSK3BDYRK1AWNT1HDAC3HDAC1 | |
| SCHEMBL20054480 | 0.86 | GSK3B (0.61) | GSK3BDYRK1AWNT1 | |
| SCHEMBL20221217 | 0.83 | SMN1; SMN2 (0.35) | GSK3BDYRK1AHDAC1AAK1LMNA | |
| SCHEMBL20054419 | 0.83 | GSK3B (0.60) | GSK3BDYRK1AWNT1HDAC3HDAC1 | |
| SCHEMBL20221552 | 0.81 | SMN1; SMN2 (0.36) | GSK3BDYRK1AAAK1MELKSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2802326-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-04-18 | — | — | EP | disclosed |