Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18462589 | 0.94 | GAA (0.33) | GAAAKR1C3AKR1C2KDM4EALDH1A1 | |
| SCHEMBL2707213 | 0.86 | GAA (0.39) | GAAALDH1A1HPGDMAPTCYP1A2 | |
| SCHEMBL18418045 | 0.82 | GAA (0.39) | GAAALDH1A1HPGDMAPTCYP1A2 | |
| SCHEMBL20055154 | 0.81 | GAA (0.32) | GAAHPGDMAPT | |
| SCHEMBL9980152 | 0.80 | GAA (0.34) | GAAHPGDMAPTCYP1A2CYP2A6 | |
| SCHEMBL13070490 | 0.80 | GAA (0.39) | GAAKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL20192479 | 0.79 | — | — | |
| SCHEMBL9980175 | 0.77 | GAA (0.34) | GAAHPGDMAPTCYP1A2CYP2A6 | |
| SCHEMBL13070649 | 0.72 | GAA (0.36) | GAAALDH1A1HPGDMAPT | |
| SCHEMBL17656324 | 0.71 | SMN1; SMN2 (0.46) | ALDH1A1HPGDMAPTTP53PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3309157-A1 | ANTIVIRAL COMPOUNDS | Gilead Pharmasset LLC (US) | 2018-04-18 | — | — | EP | disclosed |