Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | UCHL1 | P09936 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.36 |
| ▸ | KLK7 | P49862 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16001579 | 1.00 | PREP (0.42) | PREPNPC1UCHL1LMNANPSR1 | |
| SCHEMBL2709941 | 1.00 | PREP (0.42) | PREPNPC1UCHL1LMNANPSR1 | |
| SCHEMBL204525 | 1.00 | PREP (0.42) | PREPNPC1UCHL1LMNANPSR1 | |
| SCHEMBL2708422 | 0.94 | PREP (0.41) | PREPNPC1UCHL1LMNANPSR1 | |
| SCHEMBL18462482 | 0.94 | PREP (0.41) | PREPNPC1UCHL1LMNANPSR1 | |
| SCHEMBL202883 | 0.94 | PREP (0.41) | PREPNPC1UCHL1LMNANPSR1 | |
| SCHEMBL204088 | 0.87 | MEN1 (0.42) | PREPNPC1UCHL1LMNANPSR1 | |
| SCHEMBL9932688 | 0.87 | PREP (0.42) | PREPNPC1UCHL1LMNANPSR1 | |
| SCHEMBL2706740 | 0.87 | MEN1 (0.42) | PREPNPC1UCHL1LMNANPSR1 | |
| SCHEMBL14982349 | 0.87 | PREP (0.42) | PREPNPC1UCHL1LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3309157-A1 | ANTIVIRAL COMPOUNDS | Gilead Pharmasset LLC (US) | 2018-04-18 | — | — | EP | disclosed |