Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 8/20 | 0.42 |
| ▸ | CDC25B | P30305 | 8/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.39 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.39 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.39 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 4/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16027498 | 1.00 | PTPN1 (0.42) | PTPN1CDC25BPDPK1MTORSSTR1 | |
| SCHEMBL16027496 | 1.00 | PTPN1 (0.42) | PTPN1CDC25BPDPK1MTORSSTR1 | |
| SCHEMBL16076925 | 0.91 | PTPN1 (0.40) | PTPN1CDC25BPDPK1MTORSSTR1 | |
| SCHEMBL16027346 | 0.86 | PTPN1 (0.46) | PTPN1CDC25BPDPK1MTORSSTR1 | |
| SCHEMBL16027437 | 0.86 | PTPN1 (0.46) | PTPN1CDC25BPDPK1MTORSSTR1 | |
| SCHEMBL4285024 | 0.86 | PTPN1 (0.46) | PTPN1CDC25BPDPK1MTORSSTR1 | |
| SCHEMBL4283122 | 0.86 | PTPN1 (0.46) | PTPN1CDC25BPDPK1MTORSSTR1 | |
| SCHEMBL16027344 | 0.86 | PTPN1 (0.46) | PTPN1CDC25BPDPK1MTORSSTR1 | |
| SCHEMBL16027439 | 0.86 | PTPN1 (0.46) | PTPN1CDC25BPDPK1MTORSSTR1 | |
| SCHEMBL20056306 | 0.86 | PTPN1 (0.46) | PTPN1CDC25BPDPK1MTORSSTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970353-B1 | MANNOSE DERIVATIVES FOR TREATING BACTERIAL INFECTIONS | VERTEX PHARMA (US) | 2018-04-18 | — | — | EP | disclosed |