SCHEMBL2005702

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1999985	0.86	KDM4C (0.44)	ROCK1KDM4CCYP11B1CYP11B2LIMK1
	SCHEMBL3156833	0.81	SLC22A12 (0.52)	GSK3BROCK1GSK3ARPS6KA5PRKACA
	SCHEMBL2003108	0.80	KDM4C (0.45)	GPBAR1KDM4CLIMK1
	Hydrochloric Acid SCHEMBL5508376	0.79	KDM4C (0.44)	GPBAR1KDM4CLIMK1
	SCHEMBL2001092	0.75	GSK3B (0.40)	GPBAR1GSK3BGSK3ARPS6KA3KDM4C
	SCHEMBL3903670	0.75	GPBAR1 (0.47)	GPBAR1GSK3BGSK3AKDM4C
	SCHEMBL4961424	0.75	GPBAR1 (0.48)	GPBAR1GSK3BROCK1GSK3APRKACA
	SCHEMBL2003847	0.74	KDM4C (0.38)	GSK3BKDM4C
	SCHEMBL3151005	0.73	GSK3B (0.50)	GSK3BGSK3AKDM4CCYP3A4CYP2C9
	SCHEMBL3151007	0.73	GSK3B (0.50)	GSK3BGSK3AKDM4CCYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.