Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 3/20 | 0.41 |
| ▸ | CASP7 | P55210 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20057363 | 0.86 | KMT2A (0.43) | KDM4EKMT2AMEN1HSP90AA1MAPK1 | |
| SCHEMBL17254987 | 0.80 | KDM4E (0.41) | KDM4EKMT2AMEN1HSP90AA1MAPK1 | |
| SCHEMBL18205761 | 0.80 | KDM4E (0.42) | KDM4EKMT2AMEN1HSP90AA1MAPK1 | |
| SCHEMBL18057397 | 0.80 | KDM4E (0.42) | KDM4EKMT2AMEN1HSP90AA1MAPK1 | |
| SCHEMBL17255009 | 0.79 | KDM4E (0.54) | KDM4EKMT2AMEN1HSP90AA1MAPK1 | |
| SCHEMBL17255077 | 0.78 | KDM4E (0.46) | KDM4EKMT2AMEN1HSP90AA1MAPK1 | |
| SCHEMBL17254977 | 0.76 | KDM4E (0.47) | KDM4EKMT2AMEN1HSP90AA1MAPK1 | |
| SCHEMBL21208540 | 0.71 | PARP1 (0.43) | KDM4EKMT2AMEN1HSP90AA1MAPK1 | |
| SCHEMBL18213594 | 0.69 | KDM4E (0.40) | KDM4EKMT2AMEN1HSP90AA1MAPK1 | |
| SCHEMBL23160995 | 0.69 | KDM4E (0.41) | KDM4EKMT2AMEN1HSP90AA1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3140305-B1 | NOVEL COMPOSITIONS, USES AND METHODS FOR MAKING THEM | PIMERA INC (US) | 2018-04-18 | — | — | EP | disclosed |