SCHEMBL20057421

SCHEMBL20057421

CC(C)CC(NC(=O)c1ccc(C(F)(F)F)c(OCC2CC2)n1)C(N)=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 20/20 1.00
CNR1 P21554 12/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14226240 1.00 CNR2 (1.00) CNR2CNR1
SCHEMBL20057236 0.89 CNR2 (1.00) CNR2CNR1
SCHEMBL14226235 0.89 CNR2 (1.00) CNR2CNR1
SCHEMBL17764056 0.85 CNR2 (0.74) CNR2CNR1
SCHEMBL14226226 0.84 CNR2 (1.00) CNR2CNR1
SCHEMBL20057411 0.84 CNR2 (1.00) CNR2CNR1
SCHEMBL20057299 0.83 CNR2 (1.00) CNR2CNR1
SCHEMBL14226252 0.83 CNR2 (1.00) CNR2CNR1
SCHEMBL20057410 0.81 CNR2 (1.00) CNR2CNR1
SCHEMBL14226249 0.81 CNR2 (1.00) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3072886-B1 PYRIDIN-2-AMIDES USEFUL AS CB2 AGONISTS HOFFMANN LA ROCHE (CH) 2018-04-18 EP disclosed