Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.49 |
| ▸ | MTOR | P42345 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | PEPD | P12955 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 3/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15962680 | 0.84 | TRPV1 (0.52) | TRPV1PIK3CAMTORALDH1A1KDM1A | |
| SCHEMBL25202900 | 0.84 | TRPV1 (0.52) | TRPV1PIK3CAMTORKDM1AP4HTM | |
| SCHEMBL12047250 | 0.83 | TRPV1 (0.49) | TRPV1PIK3CAMTORKDM1AP4HTM | |
| SCHEMBL29618383 | 0.83 | TRPV1 (0.45) | TRPV1PIK3CAMTORALDH1A1KDM1A | |
| SCHEMBL23245943 | 0.83 | TRPV1 (0.45) | TRPV1PIK3CAMTORALDH1A1KDM1A | |
| SCHEMBL20323596 | 0.81 | TRPV1 (0.50) | TRPV1PIK3CAMTORALDH1A1KDM1A | |
| SCHEMBL29678557 | 0.79 | MAPT (0.60) | TRPV1PIK3CAMTORALDH1A1NPC1 | |
| SCHEMBL30828557 | 0.78 | P4HTM (0.57) | TRPV1PIK3CAMTORNPC1P4HTM | |
| SCHEMBL4007229 | 0.77 | NPSR1 (0.54) | PIK3CAMTORALDH1A1PEPDKIF11 | |
| SCHEMBL30350991 | 0.76 | TRPV1 (0.55) | TRPV1PIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3309146-A1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALT THEREOF | University of Tsukuba (JP) | 2018-04-18 | — | — | EP | disclosed |