Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 5/20 | 0.38 |
| ▸ | TNKS | O95271 | 3/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19107366 | 0.92 | EPHX2 (0.43) | IDO1GPR119POLBTP53THRB | |
| SCHEMBL17328219 | 0.92 | EPHX2 (0.43) | IDO1GPR119POLBTP53THRB | |
| SCHEMBL17328247 | 0.89 | EPHX2 (0.42) | IDO1GPR119EPHX2SCD5 | |
| SCHEMBL19096913 | 0.86 | HPGD (0.47) | HPGDHCRTR1HCRTR2EPHX2 | |
| SCHEMBL19107356 | 0.85 | HPGD (0.46) | HPGDIDO1GPR119POLBTP53 | |
| SCHEMBL19107367 | 0.85 | CPS1 (0.42) | GPR119TP53THRBPARP1TNKS | |
| SCHEMBL19107364 | 0.85 | PARP1 (0.43) | GPR119POLBTP53THRBPARP1 | |
| SCHEMBL19107368 | 0.85 | POLB (0.45) | IDO1POLBTP53THRBEPHX2 | |
| SCHEMBL19107365 | 0.83 | MAPK1 (0.46) | HPGDEPHX2 | |
| SCHEMBL19107361 | 0.83 | HPGD (0.44) | HPGDIDO1GPR119POLBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3149005-B1 | AMIDE DERIVATIVES OF 1-OXA-4,9-DIAZASPIRO UNDECANE COMPOUNDS HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE LABOR DR (ES) | 2018-04-18 | — | — | EP | disclosed |