Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTN3A1 | O00481 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15588696 | 1.00 | BTN3A1 (0.48) | BTN3A1ALDH1A1CA1CA2CES2 | |
| SCHEMBL851467 | 1.00 | BTN3A1 (0.48) | BTN3A1ALDH1A1CA1CA2CES2 | |
| SCHEMBL13051654 | 1.00 | BTN3A1 (0.48) | BTN3A1ALDH1A1CA1CA2CES2 | |
| SCHEMBL850882 | 1.00 | BTN3A1 (0.48) | BTN3A1ALDH1A1CA1CA2CES2 | |
| SCHEMBL851091 | 1.00 | BTN3A1 (0.48) | BTN3A1ALDH1A1CA1CA2CES2 | |
| SCHEMBL15457700 | 1.00 | BTN3A1 (0.48) | BTN3A1ALDH1A1CA1CA2CES2 | |
| SCHEMBL28842286 | 1.00 | BTN3A1 (0.48) | BTN3A1ALDH1A1CA1CA2CES2 | |
| SCHEMBL17601834 | 0.96 | CA1 (0.49) | BTN3A1ALDH1A1CA1CA2CES2 | |
| SCHEMBL16892447 | 0.93 | BTN3A1 (0.44) | BTN3A1ALDH1A1CA1CA2CES2 | |
| SCHEMBL30770430 | 0.92 | KMT2A (0.47) | ALDH1A1CA1CA2CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115103680-B | 5- (4-Aminopyrrolo [2,1-f ] [1,2,4] triazin-7-yl) -2-cyano-3, 4-dihydroxytetrahydrofuran derivatives as antiviral agents | 吉利德科学公司 | 2024-07-23 | — | — | CN | disclosed |
| WO-2023108286-A1 | PYRIDOXAL-5-PHOSPHATE (P5P) ANALOGS | CANAM BIORESEARCH INC. (CA) | 2023-06-22 | — | — | WO | disclosed |
| CN-115175735-A | Antiviral compounds | 吉利德科学公司 | 2022-10-11 | — | — | CN | disclosed |
| CN-115103680-A | 5- (4-aminopyrrolo [2,1-f ] [1,2,4] triazin-7-yl) -2-cyano-3, 4-dihydroxytetrahydrofuran derivatives as antiviral agents | 吉利德科学公司 | 2022-09-23 | — | — | CN | disclosed |
| CN-107849594-B | Deamination of organophosphorus nucleosides | 科技学专业学院有限公司 | 2022-01-18 | — | — | CN | disclosed |
| EP-2852603-B1 | D-AMINO ACID COMPOUNDS FOR LIVER DISEASE | IDENIX PHARMACEUTICALS LLC (US) | 2021-05-12 | — | — | EP | disclosed |
| CN-111848711-A | 2' -chloronucleoside analogs for HCV infection | 埃迪尼克斯医药有限责任公司 | 2020-10-30 | — | — | CN | disclosed |
| CN-111269264-A | Dioxolane analogues of uridine for the treatment of cancer | 美迪维尔公司 | 2020-06-12 | — | — | CN | disclosed |
| CN-107074826-B | Dioxolane analogues of uridine for the treatment of cancer | 美迪维尔公司 | 2020-05-22 | — | — | CN | disclosed |
| CN-110804072-A | Dioxolane analogues of uridine for the treatment of cancer | 美迪维尔公司 | 2020-02-18 | — | — | CN | disclosed |
| CN-110790789-A | Dioxolane analogues of uridine for the treatment of cancer | 美迪维尔公司 | 2020-02-14 | — | — | CN | disclosed |
| EP-2906579-B1 | 2'-CHLORO NUCLEOSIDE ANALOGS FOR HCV INFECTION | IDENIX PHARMACEUTICALS LLC (US) | 2018-04-18 | — | — | EP | disclosed |
| CN-104230985-B | Preparation method of (s)-2-[(s)-(4-nitro-phenoxy)-phenoxy-phosphoryl amino] isopropyl propionate | 北京天弘天达医药科技有限公司 | 2017-01-18 | — | — | CN | disclosed |
| CN-104230985-B | Preparation method of (s)-2-[(s)-(4-nitro-phenoxy)-phenoxy-phosphoryl amino] isopropyl propionate | 北京天弘天达医药科技有限公司 | 2017-01-18 | — | — | CN | disclosed |
| CN-104230985-A | Preparation method of (s)-2-[(s)-(4-nitro-phenoxy)-phenoxy-phosphoryl amino] isopropyl propionate | BEIJING THTD PHARMACEUTICAL TECHNOLOGY CO LTD | 2014-12-24 | — | — | CN | disclosed |
| CN-104230985-A | Preparation method of (s)-2-[(s)-(4-nitro-phenoxy)-phenoxy-phosphoryl amino] isopropyl propionate | BEIJING THTD PHARMACEUTICAL TECHNOLOGY CO LTD | 2014-12-24 | — | — | CN | disclosed |