Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29923052 | 1.00 | NOTUM (0.69) | NOTUMALDH1A1MAPTTSHRLMNA | |
| SCHEMBL13108813 | 0.84 | NOTUM (0.65) | NOTUMALDH1A1MAPTTSHRLMNA | |
| SCHEMBL15746086 | 0.84 | NOTUM (0.65) | NOTUMALDH1A1MAPTTSHRLMNA | |
| SCHEMBL15187564 | 0.84 | NOTUM (0.65) | NOTUMALDH1A1MAPTTSHRLMNA | |
| SCHEMBL9470723 | 0.84 | MEN1 (0.60) | NOTUMALDH1A1MAPTTSHRLMNA | |
| SCHEMBL29571656 | 0.84 | NOTUM (0.65) | NOTUMALDH1A1MAPTTSHRLMNA | |
| SCHEMBL17452555 | 0.84 | NOTUM (0.65) | NOTUMALDH1A1MAPTTSHRLMNA | |
| SCHEMBL22262462 | 0.83 | NOTUM (0.51) | NOTUMALDH1A1MAPTTSHRLMNA | |
| SCHEMBL22262464 | 0.83 | NOTUM (0.51) | NOTUMALDH1A1MAPTTSHRLMNA | |
| SCHEMBL29660034 | 0.83 | NOTUM (0.51) | NOTUMALDH1A1MAPTTSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3100745-B1 | NOVEL BENZODIAZEPINE DERIVATIVES | IMMUNOGEN INC (US) | 2018-04-18 | — | — | EP | disclosed |