Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRB | P23467 | 20/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21514685 | 0.92 | PTPRB (0.79) | PTPRB | |
| SCHEMBL21699540 | 0.91 | PTPRB (0.66) | PTPRB | |
| SCHEMBL679377 | 0.88 | PTPRB (1.00) | PTPRB | |
| SCHEMBL680773 | 0.88 | PTPRB (1.00) | PTPRB | |
| SCHEMBL19775587 | 0.85 | PTPRB (0.77) | PTPRB | |
| SCHEMBL19775508 | 0.84 | PTPRB (0.77) | PTPRB | |
| SCHEMBL20060102 | 0.83 | PTPRB (0.77) | PTPRB | |
| SCHEMBL28828050 | 0.83 | PTPRB (0.77) | PTPRB | |
| SCHEMBL22600467 | 0.81 | PTPRB (0.88) | PTPRB | |
| SCHEMBL679349 | 0.80 | PTPRB (1.00) | PTPRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4101297-A1 | COMPOSITIONS, FORMULATIONS AND METHODS FOR TREATING OCULAR DISEASES | Aerpio Pharmaceuticals, Inc. (US) | 2022-12-14 | — | — | EP | disclosed |
| EP-3977994-A1 | ACTIVATORS OF TIE-2 FOR USE IN TREATING INTRAOCULAR PRESSURE | Aerpio Pharmaceuticals, Inc. (US) | 2022-04-06 | — | — | EP | disclosed |
| EP-3607821-A1 | COMPOSITIONS, FORMULATIONS AND METHODS FOR TREATING OCULAR DISEASES | Aerpio Therapeutics, Inc. (US) | 2020-02-12 | — | — | EP | disclosed |
| EP-2451279-B1 | BENZOSULFONAMIDE DERIVATIVES, COMPOSITIONS THEREOF, AND THEIR USE IN PREVENTING METASTASIS OF CANCER CELLS | AERPIO THERAPEUTICS INC (US) | 2019-03-13 | — | — | EP | disclosed |
| EP-2385763-B1 | METHODS FOR TREATING VASCULAR LEAK SYNDROME | AERPIO THERAPEUTICS INC (US) | 2018-04-18 | — | — | EP | disclosed |