SCHEMBL20060784

SCHEMBL20060784

c1ccc(-c2ccc(-c3nc(-c4ccccc4)nc(-c4ccnc(-n5c6ccccc6c6cc7c8ccccc8n(-c8ccccc8)c7cc65)c4)n3)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
ATM Q13315 1/20 0.42
PDE4A P27815 2/20 0.36
PDE4B Q07343 2/20 0.36
PDE4C Q08493 2/20 0.36
PDE4D Q08499 2/20 0.36
PDE3B Q13370 2/20 0.36
PDE3A Q14432 2/20 0.36
MAPT P10636 4/20 0.34
ALDH1A1 P00352 3/20 0.34
LMNA P02545 1/20 0.34
GLA P06280 1/20 0.34
KMT2A Q03164 4/20 0.33
PTGER4 P35408 1/20 0.33
PTK2B Q14289 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
MEN1 O00255 2/20 0.33
HSP90AA1 P07900 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18253727 0.98 KDM4E (0.44) KDM4EL3MBTL1ATMPDE4APDE4B
SCHEMBL20060776 0.95 KDM4E (0.40) KDM4EL3MBTL1ATMPDE4APDE4B
SCHEMBL18253634 0.93 KDM4E (0.38) KDM4EL3MBTL1ATMPDE4APDE4B
SCHEMBL17483384 0.92 KDM4E (0.43) KDM4EL3MBTL1ATMPDE4APDE4B
SCHEMBL17483383 0.92 KDM4E (0.43) KDM4EL3MBTL1ATMPDE4APDE4B
SCHEMBL23085147 0.91 KDM4E (0.40) KDM4EL3MBTL1ATMPDE4APDE4B
SCHEMBL6373676 0.91 KDM4E (0.40) KDM4EL3MBTL1ATMPDE4APDE4B
SCHEMBL20060783 0.91 KDM4E (0.40) KDM4EL3MBTL1ATMPDE4APDE4B
SCHEMBL20060769 0.91 KDM4E (0.42) KDM4EL3MBTL1ATMPDE4APDE4B
SCHEMBL18253649 0.90 MAPK10 (0.37) KDM4EL3MBTL1ATMPDE4APDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230272275-A1 PHOSPHOROUS HOST MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-08-31 US disclosed
US-20230272275-A1 PHOSPHOROUS HOST MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-08-31 US disclosed
US-20220135875-A1 PHOSPHOROUS HOST MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2022-05-05 US disclosed
US-20210210699-A1 MULTI-COMPONENT HOST MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2021-07-08 US disclosed
US-20180105740-A1 PHOSPHOROUS HOST MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2018-04-19 US disclosed
US-20180105740-A1 PHOSPHOROUS HOST MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2018-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230272275-A1 PHOSPHOROUS HOST MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME PPA1, ENPP1, ITPA KDM4E 2389/4885L3MBTL1 1249/4885ATM 4263/4885
US-20220135875-A1 PHOSPHOROUS HOST MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME PPA1, ENPP1, ITPA KDM4E 2389/4885L3MBTL1 1249/4885ATM 4263/4885
US-20180105740-A1 PHOSPHOROUS HOST MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME PPA1, ENPP1, ITPA KDM4E 2389/4885L3MBTL1 1249/4885ATM 4263/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.