Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 18/20 | 0.84 |
| ▸ | PIK3CD | O00329 | 17/20 | 0.84 |
| ▸ | PIK3CB | P42338 | 13/20 | 0.84 |
| ▸ | PIK3CA | P42336 | 11/20 | 0.84 |
| ▸ | PIK3R1 | P27986 | 6/20 | 0.72 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.72 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.72 |
| ▸ | HTR1A | P08908 | 1/20 | 0.72 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.72 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.72 |
| ▸ | PRKDC | P78527 | 1/20 | 0.72 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.72 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.72 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.72 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16108147 | 0.92 | PIK3CG (1.00) | PIK3CGPIK3CDPIK3CBPIK3CAPIK3R1 | |
| SCHEMBL16108145 | 0.92 | PIK3CG (1.00) | PIK3CGPIK3CDPIK3CBPIK3CAPIK3R1 | |
| SCHEMBL20061549 | 0.89 | PIK3CD (0.77) | PIK3CGPIK3CDPIK3CBPIK3CAPIK3R1 | |
| SCHEMBL20067825 | 0.89 | PIK3CD (0.77) | PIK3CGPIK3CDPIK3CBPIK3CAPIK3R1 | |
| Idelalisib SCHEMBL29422886 | 0.86 | PIK3CD (0.78) | PIK3CGPIK3CDPIK3CBPIK3CAPIK3R1 | |
| Idelalisib SCHEMBL356400 | 0.86 | PIK3CD (0.78) | PIK3CGPIK3CDPIK3CBPIK3CAPIK3R1 | |
| Idelalisib SCHEMBL29354482 | 0.86 | PIK3CD (0.78) | PIK3CGPIK3CDPIK3CBPIK3CAPIK3R1 | |
| Idelalisib SCHEMBL19499808 | 0.86 | PIK3CD (0.78) | PIK3CGPIK3CDPIK3CBPIK3CAPIK3R1 | |
| Idelalisib SCHEMBL356401 | 0.86 | PIK3CD (0.78) | PIK3CGPIK3CDPIK3CBPIK3CAPIK3R1 | |
| Idelalisib SCHEMBL16822786 | 0.86 | PIK3CD (0.77) | PIK3CGPIK3CDPIK3CBPIK3CAPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312175-A1 | HETEROARYL DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING DISEASES ASSOCIATED WITH PI3 KINASES, CONTAINING SAME AS ACTIVE INGREDIENT | Korea Research Institute of Chemical Technology (KR) | 2018-04-25 | — | — | EP | disclosed |
| US-20180105527-A1 | HETEROARYL DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSTION FOR PREVENTING OR TREATING DISEASES ASSOCIATED WITH PI3 KINASES, CONTAINING SAME AS ACTIVE INGREDIENT | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2018-04-19 | — | — | US | disclosed |
| US-20180105527-A1 | HETEROARYL DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSTION FOR PREVENTING OR TREATING DISEASES ASSOCIATED WITH PI3 KINASES, CONTAINING SAME AS ACTIVE INGREDIENT | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2018-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180105527-A1 | HETEROARYL DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSTION FOR PREVENTING OR TREATING DISEASES ASSOCIATED WITH PI3 KINASES, CONTAINING SAME AS ACTIVE INGREDIENT | WEE2, WEE1, ITK | PIK3CG 19/4885PIK3CD 14/4885PIK3CB 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.