Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 20/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 12/20 | 0.48 |
| ▸ | PIK3R1 | P27986 | 10/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | PIK3R2 | O00459 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20061489 | 0.92 | PIK3CD (0.48) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA | |
| SCHEMBL20061454 | 0.90 | PIK3CD (0.53) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA | |
| SCHEMBL20061477 | 0.88 | PIK3CD (0.57) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA | |
| SCHEMBL20061491 | 0.83 | PIK3CD (0.55) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA | |
| SCHEMBL20061485 | 0.83 | PIK3CD (0.57) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA | |
| SCHEMBL20061518 | 0.82 | PIK3CD (0.52) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA | |
| SCHEMBL20061516 | 0.82 | PIK3CD (0.53) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA | |
| SCHEMBL22227599 | 0.82 | PIK3CD (0.53) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA | |
| SCHEMBL20061534 | 0.82 | PIK3CD (0.52) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA | |
| SCHEMBL20061482 | 0.82 | PIK3CD (0.60) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180105527-A1 | HETEROARYL DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSTION FOR PREVENTING OR TREATING DISEASES ASSOCIATED WITH PI3 KINASES, CONTAINING SAME AS ACTIVE INGREDIENT | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2018-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180105527-A1 | HETEROARYL DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSTION FOR PREVENTING OR TREATING DISEASES ASSOCIATED WITH PI3 KINASES, CONTAINING SAME AS ACTIVE INGREDIENT | WEE2, WEE1, ITK | PIK3CD 14/4885PIK3CG 19/4885PIK3R1 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.