SCHEMBL20062060

SCHEMBL20062060

c1ccc(-n2ccn(-c3ccccc3)c3cc4c(cc32)c2ccccc2c2ccccc2c2cccnc24)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
KAT2B Q92831 1/20 0.35
LDHA P00338 1/20 0.35
HSP90AA1 P07900 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
NPC1 O15118 1/20 0.34
PARP1 P09874 3/20 0.34
HTT P42858 1/20 0.34
KDM4E B2RXH2 5/20 0.34
PAX8 Q06710 1/20 0.34
MAPT P10636 1/20 0.34
FGFR1 P11362 2/20 0.33
GLO1 Q04760 1/20 0.33
SRC P12931 1/20 0.33
MEN1 O00255 1/20 0.33
TP53 P04637 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
ALOX15 P16050 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20062068 0.88 KDM4E (0.41) ALDH1A1L3MBTL1HTTKDM4E
SCHEMBL20062065 0.88 KDM4E (0.41) ALDH1A1L3MBTL1HTTKDM4E
SCHEMBL20062070 0.88 KDM4E (0.41) ALDH1A1L3MBTL1HTTKDM4E
SCHEMBL20062067 0.88 KDM4E (0.41) ALDH1A1L3MBTL1HTTKDM4E
SCHEMBL20062066 0.88 KDM4E (0.41) ALDH1A1L3MBTL1HTTKDM4E
SCHEMBL20062071 0.86 KDM4E (0.39) ALDH1A1L3MBTL1KDM4E
SCHEMBL20062076 0.86 KDM4E (0.39) ALDH1A1L3MBTL1KDM4E
SCHEMBL20062077 0.86 KDM4E (0.39) ALDH1A1L3MBTL1KDM4E
SCHEMBL20062074 0.86 KDM4E (0.39) ALDH1A1L3MBTL1KDM4E
SCHEMBL20062072 0.86 KDM4E (0.39) ALDH1A1L3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10608185-B2 Organic electroluminescent materials and devices UNIVERAL DISPLAY CORPORATION (US) 2020-03-31 US disclosed
US-20180108844-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2018-04-19 US disclosed
US-20180108844-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2018-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180108844-A1 Organic Electroluminescent Materials and Devices SLCO4C1, SLCO2A1, SLCO2B1 ALDH1A1 1333/4885KAT2B 2817/4885LDHA 1051/4885
US-10608185-B2 Organic electroluminescent materials and devices SLCO4C1, SLCO2A1, SLCO2B1 ALDH1A1 1333/4885KAT2B 2817/4885LDHA 1051/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.