SCHEMBL2006340

SCHEMBL2006340

Brc1ccccc1COC1CCCCO1

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 1/20 0.45
KDM4C Q9H3R0 1/20 0.43
IDO1 P14902 2/20 0.42
CARM1 Q86X55 1/20 0.41
PRMT6 Q96LA8 1/20 0.41
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.38
ALDH1A1 P00352 2/20 0.38
TSHR P16473 1/20 0.38
RECQL P46063 1/20 0.38
CYP2A13 Q16696 1/20 0.36
EP300 Q09472 1/20 0.35
CREBBP Q92793 1/20 0.35
SLC6A2 P23975 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6097349 0.88 KDM4C (0.44) TACR1KDM4CIDO1CARM1PRMT6
SCHEMBL18362480 0.87 KDM4C (0.38) TACR1KDM4CCARM1PRMT6MEN1
SCHEMBL6095923 0.86 MEN1 (0.44) TACR1KDM4CIDO1CARM1PRMT6
SCHEMBL6096051 0.86 KDM4C (0.44) TACR1KDM4CIDO1CARM1PRMT6
SCHEMBL6097200 0.86 KDM4C (0.44) TACR1KDM4CIDO1CARM1PRMT6
SCHEMBL6632939 0.86 KDM4C (0.44) TACR1KDM4CIDO1CARM1PRMT6
SCHEMBL8887331 0.86 KDM4C (0.41) TACR1KDM4CMEN1KMT2AL3MBTL1
SCHEMBL8760072 0.86 KDM4C (0.38) TACR1KDM4CCARM1PRMT6MEN1
SCHEMBL772902 0.85 KDM4C (0.53) TACR1KDM4CMEN1KMT2AL3MBTL1
SCHEMBL13490826 0.85 KDM4C (0.43) TACR1KDM4CMEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-63093779-A None JP disclosed
CN-115066428-B Boric acid derivatives 首药控股(北京)股份有限公司 2025-06-13 CN disclosed
EP-4463456-A1 THIAZOLOPYRIDYL AMIDE DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS BeiGene, Ltd. (KY) 2024-11-20 EP disclosed
CN-118510778-A Thiazolopyridylamide derivatives as inhibitors of DNA polymerase θ 百济神州有限公司 2024-08-16 CN disclosed
EP-4247369-A1 SPIROCYCLIC-SUBSTITUTED 6,7-DIHYDRO-PYRANO[2,3-D]PYRIMIDINE INHIBITORS OF KRAS G12C MUTANT Merck Sharp & Dohme LLC (US) 2023-09-27 EP disclosed
EP-3844151-B1 KRAS G12C INHIBITORS MIRATI THERAPEUTICS INC (US) 2023-08-23 EP disclosed
EP-3844151-B1 KRAS G12C INHIBITORS MIRATI THERAPEUTICS INC (US) 2023-08-23 EP disclosed
WO-2023134708-A1 THIAZOLOPYRIDYL AMIDE DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS BEIGENE , LTD. (KY) 2023-07-20 WO disclosed
CN-115066428-A Boronic acid derivatives 首药控股(北京)股份有限公司 2022-09-16 CN disclosed
WO-2022109487-A1 SPIROCYCLIC-SUBSTITUTED 6,7-DIHYDRO-PYRANO[2,3-D]PYRIMIDINE INHIBITORS OF KRAS G12C MUTANT MERCK SHARP & DOHME CORP. (US) 2022-05-27 WO disclosed
WO-1998039328-A1 SUBSTITUTED 2,4-DIAMINOPYRIMIDINES F.HOFFMANN-LA ROCHE AG (CH) 1998-09-11 WO disclosed
EP-0801054-A1 PROCESS FOR PRODUCING 2-(2-HYDROXYMETHYLPHENYL)ACETAMIDE DERIVATIVE AND INTERMEDIATE FOR THE PRODUCTION THEREOF SHIONOGI & CO., LTD. (JP) 1997-10-15 EP disclosed
CN-1145061-A Alpha-substituted phenylacetic acid derivatives, their preparation and agricultural fungicides containing the same SHIONOGI & CO (JP) 1997-03-12 CN disclosed
EP-0754672-A1 GAMMA-SUBSTITUTED PHENYLACETIC ACID DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND AGRICULTURAL BACTERICIDE CONTAINING THE SAME SHIONOGI & CO., LTD. (JP) 1997-01-22 EP disclosed
EP-0754684-A1 OXIME DERIVATIVE AND BACTERICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT SHIONOGI & CO., LTD. (JP) 1997-01-22 EP disclosed
US-4877801-A 1-Aryl-1-(1H-azol-1-ylalkyl)-1,3-dihydroisobenzofurans, related derivatives and pharmaceutical compositions thereof useful as antifungals SCHERING CORPORATION (US) 1989-10-31 US disclosed
WO-1989009771-A1 NOVEL 1-ARYL-1-(1H-IMIDAZOL-1-YLMETHYL)-1,3-DIHYDROISOBENZOFURANS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM SCHERING CORPORATION (US) 1989-10-19 WO disclosed
EP-0337019-A1 Novel 1-aryl-1-(1H-imidazol-1'-yl methyl)-1,3-dihydroisobenzofurans, their preparation and pharmaceutical compositions containing them. SCHERING CORPORATION (US) 1989-10-18 EP disclosed
JP-S6393779-A PRODUCTION OF 4,9-DIHYDRO-4-(1-METHYL-4-PIPERIDYLIDENE)-10H-BENZO(4,5)CYCLOHEPTA(1,2-B)-THIOPHEN-10-ONE OR SALT THEREOF TOYO PHARMA- KK 1988-04-25 JP disclosed
US-4737508-A 1-aryl-1-(1H-azol-1-ylalkyl)-1,3-dihydroisobenzofurans, related derivatives and pharmaceutical compositions thereof useful as antifungals SCHERING CORPORATION (US) 1988-04-12 US disclosed