Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15686723 | 1.00 | MEN1 (0.33) | MEN1CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL3244901 | 1.00 | MEN1 (0.33) | MEN1CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL14519180 | 1.00 | MEN1 (0.33) | MEN1CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL18430016 | 1.00 | MEN1 (0.33) | MEN1CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL15686716 | 1.00 | MEN1 (0.33) | MEN1CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL14519171 | 1.00 | MEN1 (0.33) | MEN1CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL20209511 | 0.93 | EPHX1 (0.36) | MEN1CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL23818479 | 0.91 | MEN1 (0.31) | MEN1CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL22003077 | 0.91 | MEN1 (0.31) | MEN1CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL22003075 | 0.86 | MEN1 (0.31) | MEN1CYP1A2CYP3A4CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018069863-A1 | 1,3 DI-SUBSTITUTED CYCLOBUTANE OR AZETIDINE DERIVATIVES AS HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2018-04-19 | — | — | WO | disclosed |