Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.36 |
| ▸ | FPR3 | P25089 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21458740 | 0.89 | PDK2 (0.44) | SMN1; SMN2PDK2MAOBGAAHPGD | |
| SCHEMBL21657308 | 0.89 | PDK2 (0.44) | SMN1; SMN2PDK2MAOBGAAHPGD | |
| SCHEMBL21071663 | 0.88 | PDK2 (0.45) | SMN1; SMN2PDK2MAOBGAAHPGD | |
| SCHEMBL21997754 | 0.86 | SMN1; SMN2 (0.42) | SMN1; SMN2PDK2MAOBGAAHPGD | |
| SCHEMBL14554544 | 0.82 | MAOB (0.49) | SMN1; SMN2PDK2MAOBGAA | |
| SCHEMBL3485869 | 0.80 | SMN1; SMN2 (0.45) | SMN1; SMN2GAAHPGDNPSR1RAB9A | |
| SCHEMBL15996418 | 0.80 | MAOB (0.51) | ACHEMAOB | |
| SCHEMBL31439940 | 0.79 | MAOB (0.52) | ACHEMAOB | |
| SCHEMBL2399096 | 0.79 | MAOB (0.52) | ACHEMAOB | |
| SCHEMBL3485508 | 0.78 | HPGD (0.51) | ACHESMN1; SMN2HPGDNPSR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018069375-A1 | NON-LINEAR SELF-IMMOLATIVE LINKERS AND CONJUGATES THEREOF | SYNTHON BIOPHARMACEUTICALS B.V. (NL) | 2018-04-19 | — | — | WO | disclosed |