SCHEMBL20069037

SCHEMBL20069037

CN1CCC(I)(C(F)(F)F)C1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DRD4 P21917 1/20 0.31
OPRM1 P35372 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22642316 0.86 HIF1A (0.31)
SCHEMBL21651948 0.74 GRIN2D (0.32) OPRM1
SCHEMBL20328004 0.72 CYP2D6 (0.32)
SCHEMBL22991866 0.70 CCR6 (0.41) DRD4OPRM1
SCHEMBL21733071 0.70
SCHEMBL25700521 0.69
SCHEMBL22838161 0.68 DRD4 (0.31) DRD4OPRM1
SCHEMBL20147958 0.68 GRIN2D (0.38) OPRM1
SCHEMBL17052869 0.68 DRD4 (0.35) DRD4OPRM1
SCHEMBL13132225 0.68 DRD4 (0.31) DRD4OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018071454-A1 SUBSTITUTED PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS RET KINASE INHIBITORS ANDREWS STEVEN W (US) 2018-04-19 WO disclosed