Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22857010 | 0.89 | RET (0.46) | RET | |
| SCHEMBL20147921 | 0.89 | RET (0.44) | RET | |
| SCHEMBL20626716 | 0.87 | RET (0.43) | RET | |
| SCHEMBL20158514 | 0.87 | RET (0.43) | RET | |
| SCHEMBL20069485 | 0.83 | CYP2C19 (0.44) | RETCYP2C19 | |
| SCHEMBL20069482 | 0.83 | RET (0.45) | RETCYP2C19 | |
| SCHEMBL20069776 | 0.82 | CYP2C19 (0.40) | RETCYP2C19 | |
| SCHEMBL20069795 | 0.82 | CYP2C19 (0.40) | RETCYP2C19 | |
| SCHEMBL20070269 | 0.81 | RET (0.46) | RETCYP2C19 | |
| SCHEMBL20069774 | 0.80 | KDM4E (0.46) | RETCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018071454-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS RET KINASE INHIBITORS | ANDREWS STEVEN W (US) | 2018-04-19 | — | — | WO | disclosed |