Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21158876 | 0.90 | RET (0.47) | RET | |
| SCHEMBL22031241 | 0.90 | RET (0.50) | RET | |
| SCHEMBL20148636 | 0.88 | RET (0.46) | RET | |
| SCHEMBL20153155 | 0.87 | RET (0.45) | RET | |
| SCHEMBL20070542 | 0.83 | RET (0.45) | RET | |
| SCHEMBL22660592 | 0.82 | RET (0.53) | RET | |
| SCHEMBL29483142 | 0.82 | RET (0.53) | RET | |
| SCHEMBL20154602 | 0.78 | RET (0.49) | RETTLR7 | |
| SCHEMBL18389829 | 0.77 | KDM4E (0.47) | RETTLR7 | |
| SCHEMBL20154601 | 0.77 | RET (0.50) | RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3753939-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS RET KINASE INHIBITORS | Array Biopharma Inc. (US) | 2020-12-23 | — | — | EP | disclosed |
| EP-3523301-B1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS RET KINASE INHIBITORS | ARRAY BIOPHARMA INC (US) | 2020-05-27 | — | — | EP | disclosed |
| WO-2018071447-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS RET KINASE INHIBITORS | ANDREWS STEVEN W (US) | 2018-04-19 | — | — | WO | disclosed |