SCHEMBL20072017

SCHEMBL20072017

Nc1ccccc(N)cccc1

nearest known ligand 0.91

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.91
MAPT P10636 6/20 0.64
MEN1 O00255 3/20 0.64
KMT2A Q03164 3/20 0.64
CYP3A4 P08684 6/20 0.57
CASP1 P29466 2/20 0.57
RECQL P46063 1/20 0.57
TDP1 Q9NUW8 3/20 0.56
TAAR1 Q96RJ0 1/20 0.56
HSD17B10 Q99714 1/20 0.56
ALOX15 P16050 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
CASP7 P55210 1/20 0.54
ALDH1A1 P00352 6/20 0.50
TP53 P04637 1/20 0.50
MAOA P21397 5/20 0.47
MAOB P27338 3/20 0.47
L3MBTL1 Q9Y468 3/20 0.47
CYP1A2 P05177 2/20 0.47
CYP2C9 P11712 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aniline SCHEMBL9755597 0.95 TSHR (1.00) TSHRMAPTMEN1KMT2ACYP3A4
Aniline SCHEMBL30471194 0.95
SCHEMBL22096536 0.95 TSHR (1.00) TSHRMAPTMEN1KMT2ACYP3A4
Aniline SCHEMBL16922171 0.95
Aniline SCHEMBL11811648 0.95 TSHR (1.00) TSHRMAPTMEN1KMT2ACYP3A4
Aniline SCHEMBL29395910 0.95
Aniline SCHEMBL30876135 0.95
Aniline SCHEMBL11803 0.95
SCHEMBL18517570 0.95 TSHR (1.00) TSHRMAPTMEN1KMT2ACYP3A4
SCHEMBL18482648 0.95 TSHR (1.00) TSHRMAPTMEN1KMT2ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180104638-A1 COMPOSITION AND SYSTEM FOR GAS STORAGE COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH OR GANISATION (AU) 2018-04-19 US disclosed