SCHEMBL200721

SCHEMBL200721

CC(C)C(O)[C@H](N)C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.65
USP2 O75604 1/20 0.50
SLCO1B1 Q9Y6L6 1/20 0.50
TP53 P04637 1/20 0.45
SLC1A3 P43003 2/20 0.42
SLC1A2 P43004 2/20 0.42
SLC1A1 P43005 2/20 0.42
PTGS1 P23219 2/20 0.36
NR1I2 O75469 1/20 0.36
ADRA1A P35348 1/20 0.36
LMNA P02545 1/20 0.36
BLM P54132 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
ACHE P22303 1/20 0.36
LTA4H P09960 1/20 0.34
GABRP O00591 2/20 0.33
GABRD O14764 2/20 0.33
GABRA1 P14867 2/20 0.33
GABRB1 P18505 2/20 0.33
GABRG2 P18507 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2030131 1.00 SLC7A5 (0.65) SLC7A5USP2SLCO1B1TP53SLC1A3
SCHEMBL2032146 1.00 SLC7A5 (0.65) SLC7A5USP2SLCO1B1TP53SLC1A3
SCHEMBL587006 1.00 SLC7A5 (0.65) SLC7A5USP2SLCO1B1TP53SLC1A3
SCHEMBL200720 1.00 SLC7A5 (0.65) SLC7A5USP2SLCO1B1TP53SLC1A3
SCHEMBL497774 1.00 SLC7A5 (0.65) SLC7A5USP2SLCO1B1TP53SLC1A3
SCHEMBL1253160 1.00 SLC7A5 (0.65) SLC7A5USP2SLCO1B1TP53SLC1A3
SCHEMBL15883792 0.84 SLC7A5 (0.59) SLC7A5USP2SLCO1B1TP53SLC1A3
SCHEMBL2405354 0.84 SLC7A5 (0.59) SLC7A5USP2SLCO1B1TP53SLC1A3
SCHEMBL1512910 0.81 SLC7A5 (0.55) SLC7A5USP2SLCO1B1TP53SLC1A3
SCHEMBL1512907 0.81 SLC7A5 (0.55) SLC7A5USP2SLCO1B1TP53SLC1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1321 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121574185-A Cyclic ester peptide compound, preparation method thereof, medicinal composition and application thereof 厦门大学 2026-02-27 CN claimed
CN-118125936-A N-acyl ethanolamide derivative, preparation method and application thereof 南京清普生物科技有限公司 2024-06-04 CN claimed
CN-117106189-A Metal organic framework artificial hydrolase and preparation method and application thereof 华南理工大学 2023-11-24 CN claimed
CN-116789760-A Cyclodecapeptide Grisgenomycins and application thereof 中国医学科学院医药生物技术研究所 2023-09-22 CN claimed
CN-108841758-A Corynebacterium glutamicum mutant and its application in L-Leu production 大连医诺生物股份有限公司 2018-11-20 CN claimed
CN-107261148-A Methylphenidate prodrug, its preparation and application 凯姆制药公司 2017-10-20 CN claimed
CN-105441501-A High-yield L-leucine strain and application of L-leucine strain in production of L-leucine with fermentation method UNIV JIANGNAN 2016-03-30 CN claimed
EP-2736510-A2 METHYLPHENIDATE-PRODRUGS, PROCESSES OF MAKING AND USING THE SAME Kempharm, Inc. (US) 2014-06-04 EP claimed
CN-103826633-A Methylphenidate prodrugs, methods of making and using the same KEMPHARM INC 2014-05-28 CN claimed
WO-2013016668-A2 METHYLPHENIDATE-PRODRUGS, PROCESSES OF MAKING AND USING THE SAME KEMPHARM INC. (US) 2013-01-31 WO claimed
EP-0913466-A2 Method for producing L-leucine Ajinomoto Co., Ltd. (JP) 1999-05-06 EP claimed
WO-1999015136-A1 REDUCTION OF HAIR GROWTH THE GILLETTE COMPANY (US) 1999-04-01 WO claimed
EP-0431323-A1 Antitumor antibiotic BU-3983T Bristol-Myers Squibb Company (US) 1991-06-12 EP claimed
EP-0030727-B1 METHOD FOR PRODUCING L-VALINE BY FERMENTATION AND METHOD FOR PRODUCING A NEW MICROORGANISM OF THE GENUS ESCHERICHIA AJINOMOTO CO., INC. (JP) 1986-10-29 EP claimed
US-4421854-A MUTANT OF ARTHROBACTER W. R. GRACE & CO. (US) 1983-12-20 US claimed
US-4421853-A Fermentative preparation of L-leucine W. R. GRACE & CO. (US) 1983-12-20 US claimed
US-4391907-A GENETIC ENGINEERING AJINOMOTO COMPANY INCORPORATED (JP) 1983-07-05 US claimed
US-4329427-A BREVIBACTERIUM CULTURE W. R. GRACE & CO. (US) 1982-05-11 US claimed
EP-0030727-A2 Method for producing L-valine by fermentation and method for producing a new microorganism of the genus Escherichia AJINOMOTO CO., INC. (JP) 1981-06-24 EP claimed
US-4228304-A ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, ANTIULCER AGENTS, BACTERICIDES, ANTITHROMBOTIC AGENTS AND FOR LIVER DISORDERS, OR AS SURFACTANTS IN DETERGENTS AND OIL ADDITIVES HISAMITSU PHARMACEUTICAL CO. INC. (JP) 1980-10-14 US claimed