SCHEMBL20072541

SCHEMBL20072541

CCCCc1ccc(-c2ccc(-c3ccccc3)cc2F)cc1

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RARB P10826 11/20 0.58
RARA P10276 2/20 0.55
RARG P13631 1/20 0.55
HSD11B1 P28845 2/20 0.50
PSMB5 P28074 1/20 0.47
MPL P40238 1/20 0.43
TAAR1 Q96RJ0 1/20 0.43
BRS3 P32247 1/20 0.41
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 1/20 0.41
MAPT P10636 1/20 0.41
MTOR P42345 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2909950 0.95 RARB (0.64) RARBRARARARGHSD11B1MEN1
SCHEMBL14175170 0.94 RARB (0.59) RARBRARARARGMPLMEN1
SCHEMBL10794766 0.91 RARB (0.50) RARBRARARARGHSD11B1TAAR1
SCHEMBL17359399 0.91 RARB (0.57) RARBRARARARGMPLMEN1
SCHEMBL14175165 0.91 RARB (0.57) RARBRARARARGMPLMEN1
SCHEMBL14175166 0.91 RARB (0.64) RARBRARARARGMPLMEN1
SCHEMBL14175164 0.91 RARB (0.64) RARBRARARARGMPLMEN1
SCHEMBL12760412 0.91 RARB (0.57) RARBRARARARGMPLMEN1
SCHEMBL9405452 0.91 RARB (0.50) RARBRARARARGHSD11B1TAAR1
SCHEMBL14175169 0.89 RARB (0.56) RARBRARARARGMPLTAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12024665-B2 Polymer-stabilized liquid crystal composition and use thereof BEIJING BAYI SPACE LCD TECHNOLOGY CO., LTD. (CN) 2024-07-02 US disclosed
US-20220389320-A1 POLYMER-STABILIZED LIQUID CRYSTAL COMPOSITION AND USE THEREOF BEIJING BAYI SPACE LCD TECHNOLOGY CO., LTD (CN) 2022-12-08 US disclosed
US-10723947-B2 Liquid crystal composition and liquid crystal display device thereof JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2020-07-28 US disclosed
US-20180105747-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE THEREOF JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2018-04-19 US disclosed