⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19444595 | 1.00 | — | — | |
| SCHEMBL3845326 | 1.00 | — | — | |
| SCHEMBL2504616 | 0.93 | MEN1 (0.32) | — | |
| SCHEMBL7863724 | 0.93 | MEN1 (0.32) | — | |
| SCHEMBL2499946 | 0.90 | MEN1 (0.31) | — | |
| SCHEMBL3837797 | 0.90 | — | — | |
| SCHEMBL21936147 | 0.86 | — | — | |
| SCHEMBL23950144 | 0.82 | — | — | |
| SCHEMBL24900902 | 0.81 | MEN1 (0.32) | — | |
| SCHEMBL20363435 | 0.81 | MEN1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10457654-B2 | Therapeutic compounds and methods of use thereof | GENENTECH, INC. (US) | 2019-10-29 | — | — | US | disclosed |
| US-20180105504-A1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2018-04-19 | — | — | US | disclosed |