SCHEMBL20074926

SCHEMBL20074926

Cc1nn(-c2cc(N)[nH]c3nn(CCC4CC4)c(-c4ccc(C#N)cc4)c3ccn2)c(C(F)F)c1Cl

nearest known ligand 0.64

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC34A1 Q06495 20/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20075033 0.91 SLC34A1 (0.61) SLC34A1
SCHEMBL20075733 0.87 SLC34A1 (0.62) SLC34A1
SCHEMBL20074909 0.87 SLC34A1 (0.59) SLC34A1
SCHEMBL20075015 0.84 SLC34A1 (0.60) SLC34A1
SCHEMBL21711362 0.78 SLC34A1 (1.00) SLC34A1
SCHEMBL20075202 0.78 SLC34A1 (0.57) SLC34A1
SCHEMBL20074994 0.77 SLC34A1 (0.59) SLC34A1
SCHEMBL20075583 0.76 SLC34A1 (0.56) SLC34A1
SCHEMBL20075732 0.73 SLC34A1 (1.00) SLC34A1
SCHEMBL20075725 0.72 SLC34A1 (0.57) SLC34A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3526212-B1 SUBSTITUTED 6-(1H-PYRAZOL-1-YL)PYRIMIDIN-4-AMINE DERIVATIVES AND USES THEREOF BAYER AG (DE) 2021-12-22 EP disclosed
WO-2018069222-A1 SUBSTITUTED 6-(1H-PYRAZOL-1-YL)PYRIMIDIN-4-AMINE DERIVATIVES AND USES THEREOF BAYER AKTIENGESELLSCHAFT (DE) 2018-04-19 WO disclosed