SCHEMBL20074987

SCHEMBL20074987

CCOC(=O)c1c(C)nn(-c2cc(Nc3c(O)c(-c4ccc(C#N)cc4)nn3C)ncn2)c1C

nearest known ligand 0.87

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC34A1 Q06495 20/20 0.87

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20075580 0.93 SLC34A1 (1.00) SLC34A1
SCHEMBL20074982 0.91 SLC34A1 (1.00) SLC34A1
SCHEMBL20074940 0.85 SLC34A1 (1.00) SLC34A1
SCHEMBL20075238 0.84 SLC34A1 (0.88) SLC34A1
SCHEMBL21711493 0.83 SLC34A1 (1.00) SLC34A1
SCHEMBL20075568 0.82 SLC34A1 (1.00) SLC34A1
SCHEMBL20075337 0.82 SLC34A1 (1.00) SLC34A1
SCHEMBL20075723 0.82 SLC34A1 (1.00) SLC34A1
SCHEMBL20075252 0.82 SLC34A1 (1.00) SLC34A1
SCHEMBL20074853 0.81 SLC34A1 (1.00) SLC34A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3526212-B1 SUBSTITUTED 6-(1H-PYRAZOL-1-YL)PYRIMIDIN-4-AMINE DERIVATIVES AND USES THEREOF BAYER AG (DE) 2021-12-22 EP disclosed
WO-2018069222-A1 SUBSTITUTED 6-(1H-PYRAZOL-1-YL)PYRIMIDIN-4-AMINE DERIVATIVES AND USES THEREOF BAYER AKTIENGESELLSCHAFT (DE) 2018-04-19 WO disclosed