Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20046759 | 0.83 | AR (0.65) | ARAAK1 | |
| SCHEMBL29855799 | 0.83 | AR (0.65) | ARAAK1 | |
| SCHEMBL31466678 | 0.83 | AR (0.65) | ARAAK1 | |
| SCHEMBL28440709 | 0.78 | AR (0.45) | AR | |
| SCHEMBL20076215 | 0.78 | AR (0.48) | AR | |
| SCHEMBL21758951 | 0.78 | AR (0.74) | AR | |
| SCHEMBL33526594 | 0.76 | LATS1 (0.35) | AAK1 | |
| SCHEMBL24652604 | 0.76 | AR (0.47) | AR | |
| SCHEMBL24652527 | 0.76 | AR (0.56) | AR | |
| SCHEMBL22047519 | 0.74 | AR (0.55) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3660004-B1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ANDROGEN RECEPTOR | ARVINAS OPERATIONS INC (US) | 2023-02-22 | — | — | EP | disclosed |
| EP-3660004-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ANDROGEN RECEPTOR | Arvinas Operations, Inc. (US) | 2020-06-03 | — | — | EP | disclosed |
| WO-2018071606-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ANDROGEN RECEPTOR | Arvinas, Inc. (US) | 2018-04-19 | — | — | WO | disclosed |